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In order to facilitate the relevant people to have a clearer understanding and positioning of the current status and development prospects of pharmaceutical glass packaging in China, to shorten the gap with the international advanced level as soon as possible, to meet the opportunities and challenges brought by the accession to the WTO for the pharmaceutical glass industry, and to promote China In order to improve the overall level of pharmaceutical preparations, this article briefly reviews the main medicinal glass packaging involved in several dosage forms.
First, the antibiotic powder bottle antibiotic powder bottles are mainly divided into molded and controlled two.
Molded antibiotic bottles: This type of product is widely used for the packaging of antibiotic powder injections. The dosage is approximately 70% of the total amount of antibiotic powder injections. The Harbin Pharmaceutical Group, Lukang Pharmaceutical Group, and Shijiazhuang Pharmaceutical Group, which have domestic antibiotics installed in the "Big Four Giants", basically all use molded antibiotic bottles. The annual consumption is about 4 billion.
In recent years, with the rapid development of the pharmaceutical industry, the level of product manufacturing and product quality have been greatly improved. In order to reduce the gap with similar products in developed countries as quickly as possible, the largest domestic manufacturer of pharmaceutical glass companies in Shandong Province, while expanding its scale, paid attention to accelerating the pace of technological transformation and increasing investment in technological transformation, it introduced an American Emme in 1997. The bottle production line of EMHART has reached and reached the advanced level of similar products in the world. Through the continuous innovation and transformation of the original technology and equipment, the company has produced thin-walled lightweight bottles and high White bottles improve the transparency and finish of the bottles.
At present, there are 10 domestically-manufactured antibiotic bottle production plants with an annual output of approximately 10 billion units. The annual output of most companies is less than 500 million, and the level of technical equipment and product quality are still quite high compared with the international advanced level of similar products. The gaps and lightweight tasks have not yet been fully realized. The traditional 800,000 units of penicillin are increasingly replaced by large doses. The emergence of various new special drugs and high-grade drugs, coupled with the competition of controlled bottles, molding of antibiotic bottles Will face the trend of lightweight, high-grade and large-scale development.
Control antibiotic bottle: This kind of product has the largest amount of use in North China Pharmaceutical Factory, with an annual consumption of about 1.2 billion. The product has developed rapidly in recent years and has gradually replaced ampoules for lyophilizers and partially replaced molded bottles. The control bottle is a secondary processed product, and its quality level depends not only on the manufacturing process, but more importantly on the quality level of the glass pipe. Therefore, enterprises with glass tube production capabilities at the same time must have certain advantages, but at present, many domestic manufacturers do not have pull tube production capabilities, resulting in a large difference in the level of product quality and fierce market competition. Compared with similar products in the world, there is also a gap in the material of glass. In addition, the level of product standards, physical quality and packaging quality have not reached the advanced level of similar international products.
From the current development trend of antibiotic powder injection at home and abroad, this product will have great potential for development. Improve the glass material, increase the strength of the bottle, improve the size of the stability, appearance quality and packaging quality, development of low expansion coefficient and the printing of the bottle, will become the future direction of development. The pharmaceutical industry stated in its development policy and objectives by 2010: “The five major formulation development output targets are expected to be: Antibiotic dispensing volume will increase by 10% per year, with a production volume of 13 billion bottles in 2000 and approximately 21 billion bottles in 2010.†Antibiotics Powder injection is one of the "five dosage forms" of medicines. Among various conventional medicines, antibiotic dosage is the largest.
From the analysis of the international and domestic market status and development needs, the use of controlled bottles has gradually increased, but molded bottles have always dominated and more than 70% of antibiotic powder injections are still in molded bottles.
The Outline of the “Tenth Five-Year†Development Plan for Pharmaceutical Packaging Industry puts forward in the development direction of each dosage form packaging: “Fluid injections (including biological and biochemical freeze-dried) should develop high-quality control bottles and light-weight molded bottles. Over a long period of time in the future, These two types of products will give full play to their unique advantages in the fierce market competition, and will inevitably appear to compete with each other and replace each other in development, and achieve greater development in mutual alternative competition."
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