Blocking iPS stem cell cultivation genes from appearing

<

A bulletin published by the iPS Cell Research Institute of Kyoto University on April 2 stated that researchers at the institution found several genes that would hinder the successful cultivation of "induced multifunctional stem cells" (iPS cells). This discovery is expected to cultivate iPS cells more efficiently.

iPS cells refer to somatic cells that have undergone gene "reorganization" to return to the state of embryonic stem cells and thus have the ability to differentiate like embryonic stem cells. In the process of cultivating iPS cells, four genes need to be implanted into mature somatic cells to make the mature cells "rejuvenate". Since Yamanaka Yamanaka, a professor at Kyoto University, invented this method, they are called the "Four Factors of Yamanaka" in Japan. However, the probability of successful iPS cell cultivation is only about 1%.

The lecturer of Kyoto University's iPS Cell Research Institute, Shinji Masai et al., Implanted the "four factors of Yamanaka" into the nerve cells of experimental rats, and studied the function of 158 genes unique to nerve cells. The formation of cultivation. If the effects of these genes are enhanced, the chance of iPS cell growth can be reduced to one-fifth of the usual level.

The researchers believe that the discovery of the aforementioned "negative" genes will help scientists grow iPS cells more efficiently. Related research results have been published in the online edition of the Proceedings of the National Academy of Sciences.

Nano Disinfecting Tissue

Disinfectant Tissue,Disinfecting Dry Tissue,Nano Disinfecting Tissue,Disposable Disinfectant Tissue

Yafeng Paper Industry Co., Ltd , https://www.tenoutissue.com