Editor's note: In the past we wanted to see the condition of the cranial cavity. By applying the Doppler effect principle, when there is relative movement between the sound source and the receiver (ie, the probe and the reflector), the frequency of the echo changes to view. Now, Japanese scientists have invented SeeDB technology, which can clearly see the scope of the organization and deepen the clarity. This combination of fructose, water, and a small amount of other chemicals is a new technology called Deep Brain Observation (SeeDB), which works by reducing the scattering of light when passing through materials with different refractive properties. Last week's "Nature-Neuroscience" online version described this technology, which also involves several other new technologies for the latest improvements in "optical clarification", including tone range and clarity. One of SeeDB's advantages is its compatibility with lipophilic dyes stored in formaldehyde, which are commonly used to track neuronal tissue; other new methods cannot. The team behind SeeDB also claims that this method works faster, non-toxic and easy to handle, without distorting tissue samples. Meng-TsenKe, a research team member, lead author and neuroscientist of the Developmental Biology Research Center of the Kobe Institute of Physics and Chemistry in Japan, said that researchers will be able to choose the clarification technology that is most suitable for the research goal.
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